For estimation of metoclopramide in pharmaceutical dosage form, a simple, accurate and precise area under curve spectrophotometric method was developed. ââ?¬Å?The area under two points on the mixture spectra is directly proportional to the concentration of the component of interestââ?¬Â is the AUC curve. The area selected for estimation of metoclopramide was between 262 to 282 nm. The method represented regression coefficient (r2= 0.999) at concentration rang 5-25 Ã?µg/ml. Estimation of the drugs was found upto 100 % representing the accuracy of the method. The recovery of the metoclopramide was found upto 100 %. Validation of the proposed method was carried out for its accuracy, precision and specificity according to ICH Q2 (R1) guidelines. The developed methods can be successfully applied in routine work for the estimation of metoclopramide in its pharmaceutical dosage form.Ã?©Ã?²
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